Sherlock’s Diseases of the Liver and Biliary System, 13th Edition

A new, fully updated edition of the world’s most famous book on liver diseases—with updating of all areas and inclusion of new specific topics, by internationally renowned specialists

This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world’s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock’s Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock’s unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors’ experience, the hallmark of this book. Based on these elements, the 12^th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category.

Sherlock’s Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website.

• Internationally recognized and loved, world-renowned hepatology book, first published in 1955
• Takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock’s clarity and legacy of presentation
• Full colour throughout with 700 illustrative figures
• Wide faculty of international contributors

Sherlock’s Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.

Table of Contents

Chapter 1 Anatomy And Function
Chapter 2 Liver Function In Health And Disease: Clinical Application Of Liver Tests
Chapter 3 Biopsy Of The Liver
Chapter 4 Coagulation In Cirrhosis
Chapter 5 Acute Liver Failure
Chapter 6 Hepatic Fibrogenesis
Chapter 7 Non‐Invasive Assessment Of Fibrosis And Cirrhosis
Chapter 8 Hepatic Cirrhosis
Chapter 9 Ascites
Chapter 10 Hepatic Encephalopathy In Patients With Cirrhosis
Chapter 11 Portal Hypertension In Cirrhosis
Chapter 12 Vascular Disorders Of The Liver And Extrahepatic Portal Hypertension
Chapter 13 Jaundice And Cholestasis
Chapter 14 Gallstones And Benign Biliary Disease
Chapter 15 Malignant Biliary Diseases
Chapter 16 Fibropolycystic Liver Diseases And Congenital Biliary Abnormalities
Chapter 17 Primary Biliary Cholangitis
Chapter 18 Sclerosing Cholangitis
Chapter 19 Autoimmune Hepatitis And Overlap Syndromes
Chapter 20 Enterically Transmitted Viral Hepatitis: Hepatitis A And Hepatitis E
Chapter 21 Hepatitis B
Chapter 22 Hepatitis D
Chapter 23 Hepatitis C
Chapter 24 Drug‐Induced Liver Injury
Chapter 25 Alcohol And The Liver
Chapter 26 Iron Overload States
Chapter 27 Wilson Disease
Chapter 28 Non‐Alcoholic Fatty Liver Disease
Chapter 29 Nutrition And Chronic Liver Disease
Chapter 30 Pregnancy And The Liver
Chapter 31 The Liver In The Neonate, In Infancy, And Childhood
Chapter 32 The Liver In Systemic Diseases
Chapter 33 The Liver In Infections
Chapter 34 Imaging Of The Liver And Diagnostic Approach Of Space‐Occupying Lesions
Chapter 35 Benign Liver Tumours
Chapter 36 Primary Malignant Neoplasms Of The Liver
Chapter 37 Hepatic Transplantation
Chapter 38 Hepatic Transplantation And Hbv, Hcv, And Hiv Infections